In the paper the problem of DNA sequencing by hybridization (SBH) is considered.With the developed software, MELTEM, several assembling procedures are used to ease acollecting a subset of oligonucleotides that would melt under practically identical conditionsin a hybridization experiment. Some clustering approaches implemented in the program arecompared. The algorithms of MELTEM are presented as well as the selected examples of amelting temperature analysis.
|Parameter Analysis of Clusters of Melting Temperatures of Dna Chains
Błażewicz Jacek Gwóźdź Łukasz, Kasprzak Marta, Przysucha Marcin
Błażewicz Jacek Kaczmarek Janusz, Marta Kasprzak, Jan Węglarz
Błażewicz Jacek Dill Ken, Łukasiak Piotr, Miłostan Maciej
Błażewicz Jacek Hammer P., Łukasiak P.
Błażewicz Jacek Machowiak M., Mounie G., Trystram D.