Title:

PARAMETER ANALYSIS OF CLUSTERS OF MELTING TEMPERATURES OF DNA CHAINS

Creator:

Błażewicz Jacek

Contributor:

Cysewska-Sobusiak Anna, Lerczak Agata, Kasprzak Marta, Markiewicz Wojciech T.

Tags:

DNA sequencing, clustering, hybridization experiment.

Abstract:

In the paper the problem of DNA sequencing by hybridization (SBH) is considered.With the developed software, MELTEM, several assembling procedures are used to ease acollecting a subset of oligonucleotides that would melt under practically identical conditionsin a hybridization experiment. Some clustering approaches implemented in the program arecompared. The algorithms of MELTEM are presented as well as the selected examples of amelting temperature analysis.

Place of publishing:

Poznań

Publisher:

OWN

Format:

application/pdf

Language:

eng